This methylation profile is currently acquired at the MBL stage3 and remains comparatively stable after a while. Nonetheless, some CLL have intratumor variability in sure locations, which can alter the expression of several genes and facilitate tumor evolution.seventy one Of note, this variability is larger in U-CLL than in M-CLL https://louisqhuix.blog-a-story.com/12831810/the-definitive-guide-to-situs-judi-mbl77