There is a launch of norepinephrine from the descending inhibitory bulbospinal neurons that binds to alpha-2-receptors while in the dorsal horn to lower afferent discomfort transmission and produce analgesia. Hence, medications like clonidine that goal alpha-2 receptors can affect the transmission of discomfort. Clonidine is an extended-term medication. It https://vono704luz7.wikipublicity.com/user